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Group Members
Dr. Klaus Spohr (PI)
Dr. Viorel Nastasa
Dr. Domenico Doria
Alexandru Magureanu
Project Work
a fundamental learning derived from the project which informes future studies.
[1] M. W. Mortensen et al. “Next Generation Adoptive Immunotherapy - Human T Cells as Carriers of Therapeutic Nanoparticles”. In: Journal of Nanoscience and Nanotechnology 7.12 (2007), pages 4575–4580. DOI: doi:10.1166/jnn.2007.18108
[2] J. R. Lindner. “Microbubbles in medical imaging: current applications and future directions”. In: Nature Reviews Drug Discovery 3.6 (June 2004), pages 527–533. DOI: 10.1038/nrd1417.
[3] J. Collis et al. “Cavitation microstreaming and stress fields created by microbubbles”. In: Ultrasonics 50.2 (Feb. 2010), pages 273–279. DOI: 10.1016/j.ultras. 2009.10.002.
[4] F. Prada et al. “Quantitative analysis of in-vivo microbubble distribution in the human brain”. In: Scientific Reports 11.1 (June 2021), page 11797. ISSN: 2045-2322. DOI: 10.1038/s41598-021-91252-w.
[5] Z. Wang et al. “Analytical solutions of the Rayleigh-Plesset equation for N-dimensional spherical bubbles”. In: Science China Physics, Mechanics & Astronomy 60.10 (Aug. 2017), page 104721. ISSN: 1869-1927. DOI: 10.1007/s11433-017-9074-x.
[6] M. W. Mortensen et al. “Functionalization and Cellular Uptake of Boron Carbide Nanoparticles. The First Step toward T Cell-Guided Boron Neutron Capture Therapy”. In: Bioconjugate Chemistry 17.2 (Mar. 2006), pages 284–290. ISSN: 1043- 1802. DOI: 10.1021/bc050206v.
[7] J. P. Fisher et al. “γδ T cells for cancer immunotherapy”. In: OncoImmunology 3.1 (Jan. 2014), e27572. DOI: 10.4161/onci.27572.
[8] J. C. Ribot et al. “γδ T cells in tissue physiology and surveillance”. In: Nature Reviews Immunology 21.4 (Oct. 2020), pages 221–232. DOI: 10.1038/s41577-020- 00452-4.
[9] D. Kabelitz et al. “Cancer immunotherapy with γδ T cells: many paths ahead of us”. In: Cellular & Molecular Immunology 17.9 (July 2020), pages 925–939. DOI: 10.1038/s41423-020-0504-x.
[10] M. Leek et al. “Patent: MODIFIED GAMMA DELTA T CELLS AND USES THEREOF”. In: Espacenet (www.epsacenet.com) WO2016166544A1 (2016).
[11] J. Doyen et al. “Early Toxicities After High Dose Rate Proton Therapy in Cancer Treatments”. In: Frontiers in Oncology 10 (2021), page 2963. DOI: 10.3389/fonc. 2020.613089.
[12] S. van de Water et al. “Towards FLASH proton therapy: the impact of treatment planning and machine characteristics on achievable dose rates”. In: Acta Oncologica 58.10 (June 2019), pages 1463–1469. DOI: 10 . 1080 / 0284186x . 2019 . 1627416.
[13] S. R. Mirfayzi et al. “Proof-of-principle experiment for laser-driven cold neutron source”. In: Scientific Reports 10.1 (Nov. 2020), page 20157. ISSN: 2045-2322. DOI: 10.1038/s41598-020-77086-y.
[14] D. Doria. Private Communication. 2021.
[15] S. Balascuta. Private Communication. 2021.
[1] M. W. Mortensen et al. “Next Generation Adoptive Immunotherapy - Human T Cells as Carriers of Therapeutic Nanoparticles”. In: Journal of Nanoscience and Nanotechnology 7.12 (2007), pages 4575–4580. DOI: doi:10.1166/jnn.2007.18108
[2] J. R. Lindner. “Microbubbles in medical imaging: current applications and future directions”. In: Nature Reviews Drug Discovery 3.6 (June 2004), pages 527–533. DOI: 10.1038/nrd1417.
[3] J. Collis et al. “Cavitation microstreaming and stress fields created by microbubbles”. In: Ultrasonics 50.2 (Feb. 2010), pages 273–279. DOI: 10.1016/j.ultras. 2009.10.002.
[4] F. Prada et al. “Quantitative analysis of in-vivo microbubble distribution in the human brain”. In: Scientific Reports 11.1 (June 2021), page 11797. ISSN: 2045-2322. DOI: 10.1038/s41598-021-91252-w.
[5] Z. Wang et al. “Analytical solutions of the Rayleigh-Plesset equation for N-dimensional spherical bubbles”. In: Science China Physics, Mechanics & Astronomy 60.10 (Aug. 2017), page 104721. ISSN: 1869-1927. DOI: 10.1007/s11433-017-9074-x.
[6] M. W. Mortensen et al. “Functionalization and Cellular Uptake of Boron Carbide Nanoparticles. The First Step toward T Cell-Guided Boron Neutron Capture Therapy”. In: Bioconjugate Chemistry 17.2 (Mar. 2006), pages 284–290. ISSN: 1043- 1802. DOI: 10.1021/bc050206v.
[7] J. P. Fisher et al. “γδ T cells for cancer immunotherapy”. In: OncoImmunology 3.1 (Jan. 2014), e27572. DOI: 10.4161/onci.27572.
[8] J. C. Ribot et al. “γδ T cells in tissue physiology and surveillance”. In: Nature Reviews Immunology 21.4 (Oct. 2020), pages 221–232. DOI: 10.1038/s41577-020- 00452-4.
[9] D. Kabelitz et al. “Cancer immunotherapy with γδ T cells: many paths ahead of us”. In: Cellular & Molecular Immunology 17.9 (July 2020), pages 925–939. DOI: 10.1038/s41423-020-0504-x.
[10] M. Leek et al. “Patent: MODIFIED GAMMA DELTA T CELLS AND USES THEREOF”. In: Espacenet (www.epsacenet.com) WO2016166544A1 (2016).
[11] J. Doyen et al. “Early Toxicities After High Dose Rate Proton Therapy in Cancer Treatments”. In: Frontiers in Oncology 10 (2021), page 2963. DOI: 10.3389/fonc. 2020.613089.
[12] S. van de Water et al. “Towards FLASH proton therapy: the impact of treatment planning and machine characteristics on achievable dose rates”. In: Acta Oncologica 58.10 (June 2019), pages 1463–1469. DOI: 10 . 1080 / 0284186x . 2019 . 1627416.
[13] S. R. Mirfayzi et al. “Proof-of-principle experiment for laser-driven cold neutron source”. In: Scientific Reports 10.1 (Nov. 2020), page 20157. ISSN: 2045-2322. DOI: 10.1038/s41598-020-77086-y.
[14] D. Doria. Private Communication. 2021.
[15] S. Balascuta. Private Communication. 2021.
References
[1] M. W. Mortensen et al. “Next Generation Adoptive Immunotherapy - Human T Cells as Carriers of Therapeutic Nanoparticles”. In: Journal of Nanoscience and Nanotechnology 7.12 (2007), pages 4575–4580. DOI: doi:10.1166/jnn.2007.18108
[2] J. R. Lindner. “Microbubbles in medical imaging: current applications and future directions”. In: Nature Reviews Drug Discovery 3.6 (June 2004), pages 527–533. DOI: 10.1038/nrd1417.
[3] J. Collis et al. “Cavitation microstreaming and stress fields created by microbubbles”. In: Ultrasonics 50.2 (Feb. 2010), pages 273–279. DOI: 10.1016/j.ultras. 2009.10.002.
[4] F. Prada et al. “Quantitative analysis of in-vivo microbubble distribution in the human brain”. In: Scientific Reports 11.1 (June 2021), page 11797. ISSN: 2045-2322. DOI: 10.1038/s41598-021-91252-w.
[5] Z. Wang et al. “Analytical solutions of the Rayleigh-Plesset equation for N-dimensional spherical bubbles”. In: Science China Physics, Mechanics & Astronomy 60.10 (Aug. 2017), page 104721. ISSN: 1869-1927. DOI: 10.1007/s11433-017-9074-x.
[6] M. W. Mortensen et al. “Functionalization and Cellular Uptake of Boron Carbide Nanoparticles. The First Step toward T Cell-Guided Boron Neutron Capture Therapy”. In: Bioconjugate Chemistry 17.2 (Mar. 2006), pages 284–290. ISSN: 1043- 1802. DOI: 10.1021/bc050206v.
[7] J. P. Fisher et al. “γδ T cells for cancer immunotherapy”. In: OncoImmunology 3.1 (Jan. 2014), e27572. DOI: 10.4161/onci.27572.
[8] J. C. Ribot et al. “γδ T cells in tissue physiology and surveillance”. In: Nature Reviews Immunology 21.4 (Oct. 2020), pages 221–232. DOI: 10.1038/s41577-020- 00452-4.
[9] D. Kabelitz et al. “Cancer immunotherapy with γδ T cells: many paths ahead of us”. In: Cellular & Molecular Immunology 17.9 (July 2020), pages 925–939. DOI: 10.1038/s41423-020-0504-x.
[10] M. Leek et al. “Patent: MODIFIED GAMMA DELTA T CELLS AND USES THEREOF”. In: Espacenet (www.epsacenet.com) WO2016166544A1 (2016).
[11] J. Doyen et al. “Early Toxicities After High Dose Rate Proton Therapy in Cancer Treatments”. In: Frontiers in Oncology 10 (2021), page 2963. DOI: 10.3389/fonc. 2020.613089.
[12] S. van de Water et al. “Towards FLASH proton therapy: the impact of treatment planning and machine characteristics on achievable dose rates”. In: Acta Oncologica 58.10 (June 2019), pages 1463–1469. DOI: 10 . 1080 / 0284186x . 2019 . 1627416.
[13] S. R. Mirfayzi et al. “Proof-of-principle experiment for laser-driven cold neutron source”. In: Scientific Reports 10.1 (Nov. 2020), page 20157. ISSN: 2045-2322. DOI: 10.1038/s41598-020-77086-y.
[14] D. Doria. Private Communication. 2021.
[15] S. Balascuta. Private Communication. 2021.